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ASGR2 (Asialoglycoprotein Receptor 2) (7N1) Mouse Monoclonal antibody

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产品基本信息

产品货号
BD-PE0960
产品名称
ASGR2 (Asialoglycoprotein Receptor 2) (7N1) Mouse Monoclonal antibody
类别
常规抗体
基因名称
Asialoglycoprotein Receptor 2
推荐应用
WB
反应种属
Human
存储缓冲液
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
免疫原
Full length human recombinant protein of human ASGR2(NP_001172) produced in HEK293T cell.
稀释度
WB 1:4000, IF 1:100
预测分子量
35kDa
运输及保存条件
-20°C/1 year
宿主
Mouse
同种型
IgG2b
背景介绍
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
期货
现货
纯化
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunofluorescent staining of HeLa cells using anti-ASGR2 mouse monoclonal antibody (BD-PE0960).

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ASGR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ASGR2. Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.

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