产品名称
SNRK Rabbit Polyclonal Antibody
蛋白名称
SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NRH2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NRH2/entry
Mouse Swissprot No.
Q8VDU5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VDU5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q63553
免疫原
Synthesized peptide derived from part region of human protein
特异性
SNRK Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009],
组织表达
Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis.
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-173 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,tissue specificity:Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
