产品名称
NRK Rabbit Polyclonal Antibody
蛋白名称
Nik-related protein kinase (EC 2.7.11.1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q7Z2Y5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7Z2Y5/entry
Mouse Swissprot No.
Q9R0G8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R0G8
免疫原
Synthesized peptide derived from part region of human protein
特异性
NRK Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Nik related kinase(NRK) Homo sapiens The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010],
组织表达
Fetal kidney,Ovary,Placenta,
细胞定位
cytoplasm,integral component of membrane,
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
