产品名称
B2L13 Rabbit Polyclonal Antibody
蛋白名称
Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BXK5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BXK5/entry
Mouse Swissprot No.
P59017
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P59017
免疫原
Synthesized peptide derived from part region of human protein
特异性
B2L13 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012],
组织表达
Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.
细胞定位
[Isoform 2]: Mitochondrion membrane ; Single-pass membrane protein . Nucleus .; [Isoform 1]: Nucleus .
功能
alternative products:Experimental confirmation may be lacking for some isoforms,function:May promote the activation of caspase-3 and apoptosis.,similarity:Belongs to the Bcl-2 family.,subunit:Monomer.,tissue specificity:Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.