产品名称
RASEF Rabbit Polyclonal Antibody
蛋白名称
Ras and EF-hand domain-containing protein (Ras-related protein Rab-45)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8IZ41
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IZ41/entry
Mouse Swissprot No.
Q5RI75
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5RI75
免疫原
Synthesized peptide derived from part region of human protein
特异性
RASEF Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012],
组织表达
Down-regulated in cutaneous melanoma cells but not in breast cancer cells.
细胞定位
Cytoplasm, perinuclear region .
功能
function:Binds predominantly GDP, and also GTP.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Down-regulated in cutaneous melanoma cells but not in breast cancer cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
