产品名称
NGAP Rabbit Polyclonal Antibody
蛋白名称
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UJF2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UJF2/entry
免疫原
Synthesized peptide derived from part region of human protein
特异性
NGAP Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
组织表达
Brain,Epithelium,Heart,Muscle,PCR rescued clones,Peripheral Nervous System,
细胞定位
cytoplasm,cytosol,intrinsic component of the cytoplasmic side of the plasma membrane,
功能
function:Inhibitory regulator of the Ras-cyclic AMP pathway.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GAP domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.