BD-PN1855

RASA2 Rabbit Polyclonal Antibody

常规抗体

RASA2 GAP1M RASGAP

Ras GTPase-activating protein 2 (GAP1m)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

5922

Q15283

https://www.uniprot.org/uniprotkb/Q15283/entry

P58069

http://www.uniprot.org/uniprot/P58069

Q63713

http://www.uniprot.org/uniprot/O54941Q63713

Synthesized peptide derived from part region of human protein

RASA2 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000

93kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

Blood,Brain,

Cytoplasm. Cytoplasm, perinuclear region.

MAPK_ERK_Growth;MAPK_G_Protein;

function:Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 2 C2 domains.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.