BD-PN1844

ATRN Rabbit Polyclonal Antibody

常规抗体

ATRN KIAA0548 MGCA

Attractin (DPPT-L) (Mahogany homolog)

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

8455

O75882

https://www.uniprot.org/uniprotkb/O75882/entry

Q9WU60

http://www.uniprot.org/uniprot/Q9WU60

Q99J86

http://www.uniprot.org/uniprot/O54941Q99J86

Synthesized peptide derived from part region of human protein

ATRN Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

157kD

-20°C/1 year

Polyclonal, Rabbit,IgG

attractin(ATRN) Homo sapiens This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016],

Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes.

[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .

function:Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system.,induction:Activation of peripheral blood leukocytes with phytohemagglutinin induces strong expression of the membrane isoform followed by the release of the secreted isoform.,online information:Attractin-2,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 CUB domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 laminin EGF-like domains.,similarity:Contains 6 Kelch repeats.,tissue specificity:Expressed and secreted by activated T lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2/secreted is the major isoform in peripheral blood leukocytes.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.