BD-PE0479-FOLR2 (16I8) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

FOLR2 (16I8) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE0479

产品名称

FOLR2 (16I8) Mouse Monoclonal antibody

类别

常规抗体

基因名称

FOLR2

推荐应用

反应种属

Human

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Human recombinant protein fragment corresponding to amino acids 20-221 of human FOLR2(NP_000794) produced in E.coli.

稀释度

WB 1:2000, IHC 1:150

预测分子量

29.1kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG1

背景介绍

The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-FOLR2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, BD-PE0479) (1:150)

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-FOLR2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, BD-PE0479) (1:150)

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FOLR2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, BD-PE0479) (1:150)

Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-FOLR2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, BD-PE0479) (1:150)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOLR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOLR2 (1:2000). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.