产品名称
SOX4 Rabbit Polyclonal Antibody
蛋白名称
Transcription factor SOX-4
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q06945
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q06945/entry
Mouse Swissprot No.
Q06831
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q06831
免疫原
Synthesized peptide derived from part region of human protein
特异性
SOX4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
SRY-box 4(SOX4) Homo sapiens This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008],
组织表达
Testis, brain, and heart.
功能
function:Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Interacts with UBE2I.,tissue specificity:Testis, brain, and heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
