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SOD2 (Superoxide Dismutase 2) (13M18) Mouse Monoclonal antibody

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产品基本信息

产品货号
BD-PE0406
产品名称
SOD2 (Superoxide Dismutase 2) (13M18) Mouse Monoclonal antibody
类别
常规抗体
基因名称
SOD2
推荐应用
WB
反应种属
Human,Dog,Mouse,Rat
存储缓冲液
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
免疫原
Full length human recombinant protein of human SOD2 (NP_000627) produced in HEK293T cell.
稀释度
WB 1:500~2000
预测分子量
22.2kDa
运输及保存条件
-20°C/1 year
宿主
Mouse
同种型
IgG1
背景介绍
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
期货
现货
纯化
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SOD2 monoclonal antibody.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SOD2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SOD2 (Cat# BD-PE0406). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.

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