产品名称
PO3F2 Rabbit Polyclonal Antibody
基因名称
POU3F2 BRN2 OCT7 OTF7
蛋白名称
POU domain, class 3, transcription factor 2 (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Brn-2) (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Octamer-binding protein 7) (Oct-7) (Octamer-binding transcription factor 7) (OTF-7)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P20265
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P20265/entry
Mouse Swissprot No.
P31360
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P31360
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P56222
免疫原
Synthesized peptide derived from part region of human protein
特异性
PO3F2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012],
组织表达
Expressed specifically in the neuroectodermal cell lineage.
功能
function:Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters.,similarity:Belongs to the POU transcription factor family. Class-3 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with PQBP1.,tissue specificity:Expressed specifically in the neuroectodermal cell lineage.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
