BD-PE0331-PMS2 (14P7) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

PMS2 (14P7) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE0331

产品名称

PMS2 (14P7) Mouse Monoclonal antibody

类别

常规抗体

基因名称

PMS2

推荐应用

反应种属

Human

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.

稀释度

WB 1:500, IHC 1:150, IF: 1:100

预测分子量

95.6kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG2b

背景介绍

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE0331)

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE0331)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE0331)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE0331)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE0331)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE0331)

Immunofluorescent staining of HeLa cells using anti-PMS2 mouse monoclonal antibody (BD-PE0331).

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PMS2(Cat# BD-PE0331). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.