产品名称
DMBX1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/127343
Human Swissprot No.
Q8NFW5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NFW5/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/140477
Mouse Swissprot No.
Q91ZK4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91ZK4
免疫原
Synthesized peptide derived from human DMBX1 AA range: 88-138
特异性
This antibody detects endogenous levels of DMBX1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
功能
function:Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,subunit:Homodimer or heterodimer. Forms heterodimers with OTX2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
