BD-PE0316

F2 (15Y17) Mouse Monoclonal antibody

常规抗体

F2

WB

Human

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Human recombinant protein fragment corresponding to amino acids 44-622 of human F2 (NP_000497) produced in HEK293T cell.

WB 1:500

70.01kDa

-20°C/1 year

Mouse

IgG2a

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)