产品名称
CANT1 Rabbit Polyclonal Antibody
蛋白名称
Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8WVQ1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WVQ1/entry
Mouse Swissprot No.
Q8VCF1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VCF1
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q8K4Y7
免疫原
Synthesized peptide derived from part region of human protein
特异性
CANT1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
calcium activated nucleotidase 1(CANT1) Homo sapiens This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Cell membrane . Processed form: Secreted.
信号通路
Purine metabolism;Pyrimidine metabolism;
功能
catalytic activity:A nucleoside diphosphate + H(2)O = a nucleotide + phosphate.,cofactor:Calcium.,function:Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.,miscellaneous:Not inhibited by azide.,PTM:N-glycosylated.,similarity:Belongs to the apyrase family.,subcellular location:Processed form: Secreted.,subunit:Monomer.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
