BD-PE0237-TYR (3K18) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

TYR (3K18) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE0237

产品名称

TYR (3K18) Mouse Monoclonal antibody

类别

常规抗体

基因名称

TYR

推荐应用

反应种属

Human,Mouse,Rat

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Human recombinant protein fragment corresponding to amino acids 19-320 of human TYR (NP_000363) produced in E.coli.

稀释度

WB 1:2000, IHC 1:150

预测分子量

58.3kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG1

背景介绍

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TYR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, BD-PE0237)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TYR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TYR antibody (Cat# BD-PE0237). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.