BD-PE0164

MICA (13M1) Mouse Monoclonal antibody

常规抗体

MICA

WB

Human

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human MICA (NP_000238) produced in HEK293T cell.

WB 1:500-1000, FCM 1:100

42.9kDa

-20°C/1 year

Mouse

IgG1

This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)