产品名称
SYCP1 Rabbit Polyclonal Antibody
蛋白名称
Synaptonemal complex protein 1 (SCP-1) (Cancer/testis antigen 8) (CT8)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q15431
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15431/entry
Mouse Swissprot No.
Q62209
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q62209
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q03410
免疫原
Synthesized peptide derived from part region of human protein
特异性
SYCP1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:Consists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity.,function:Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.,subcellular location:In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex.,subunit:Found in a complex with SYCE1 and SYCE2. Interacts with SYCE1 and SYCE2.,tissue specificity:Testis.,
细胞定位
Nucleus . Chromosome . Chromosome, centromere . In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex (By similarity). Only rarely detected at centromeres during leptotene and zygotene. Detected at centromeres during mid-diplotene, when it is no longer present along chromosome arms. No longer detected at centromeres at later stages of meiosis (By similarity). .
功能
domain:Consists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity.,function:Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.,subcellular location:In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex.,subunit:Found in a complex with SYCE1 and SYCE2. Interacts with SYCE1 and SYCE2.,tissue specificity:Testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
