产品名称
CANT1 Rabbit Polyclonal Antibody
蛋白名称
Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8WVQ1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WVQ1/entry
Mouse Swissprot No.
Q8VCF1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VCF1
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q8K4Y7
免疫原
Synthesized peptide derived from part region of human protein
特异性
CANT1 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
calcium activated nucleotidase 1(CANT1) Homo sapiens This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Cell membrane . Processed form: Secreted.
信号通路
Purine metabolism;Pyrimidine metabolism;
功能
catalytic activity:A nucleoside diphosphate + H(2)O = a nucleotide + phosphate.,cofactor:Calcium.,function:Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.,miscellaneous:Not inhibited by azide.,PTM:N-glycosylated.,similarity:Belongs to the apyrase family.,subcellular location:Processed form: Secreted.,subunit:Monomer.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
