产品名称
MCM9 Rabbit Polyclonal Antibody
蛋白名称
DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NXL9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NXL9/entry
Mouse Swissprot No.
Q2KHI9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q2KHI9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941F1M5F3
免疫原
Synthesized peptide derived from part region of human protein
特异性
MCM9 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010],
细胞定位
Nucleus . Chromosome . Colocalizes to nuclear foci with RPA1 following DNA damage (PubMed:23401855). Localizes to double-stranded DNA breaks (PubMed:23401855). Recruited to chromatin by MSH2 (PubMed:26300262). .
功能
similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
