BD-PE0069

EPOR (15L1) Mouse Monoclonal antibody

常规抗体

EPOR

WB

Human

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Human recombinant protein fragment corresponding to amino acids 25-250 of human EPOR (NP_000112) produced in E.coli.

WB 1:2000, IHC 1:150

-20°C/1 year

Mouse

IgG2a

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)