产品名称
TBA8 Rabbit Polyclonal Antibody
蛋白名称
Tubulin alpha-8 chain (Alpha-tubulin 8) (Tubulin alpha chain-like 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NY65
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NY65/entry
Mouse Swissprot No.
Q9JJZ2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JJZ2
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6AY56
免疫原
Synthesized peptide derived from part region of human protein
特异性
TBA8 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
TUBA8 encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants. TUBA8 (Tubulin Alpha 8) is a Protein Coding gene. Diseases associated with TUBA8 include Cortical Dysplasia, Complex, With Other Brain Malformations 8 and Optic Nerve Hypoplasia. Among its related pathways are Development Slit-Robo signaling and Cytoskeleton remodeling Neurofilaments.
组织表达
Preferentially expressed in heart, skeletal muscle and testis. Expressed at low levels in the developing brain.
细胞定位
Cytoplasm, cytoskeleton.
信号通路
Gap junction;Pathogenic Escherichia coli infection;
功能
protein complex assembly,?microtubule-based process,?microtubule-based movement,?cellular macromolecular complex subunit organization,?cellular macromolecular complex assembly,?cellular protein complex assembly,?macromolecular complex subunit organization,?protein polymerization,?macromolecular complex assembly,?protein complex biogenesis,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
