产品名称
MCM9 Rabbit Polyclonal Antibody
蛋白名称
DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NXL9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NXL9/entry
Mouse Swissprot No.
Q2KHI9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q2KHI9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941F1M5F3
免疫原
Synthesized peptide derived from part region of human protein
特异性
MCM9 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010],
细胞定位
Nucleus . Chromosome . Colocalizes to nuclear foci with RPA1 following DNA damage (PubMed:23401855). Localizes to double-stranded DNA breaks (PubMed:23401855). Recruited to chromatin by MSH2 (PubMed:26300262). .
功能
similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
