RM3772

NFkB p100 (6G14) Rabbit Monoclonal Antibody

p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100

常规抗体

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Recombinant protein of human NFkB p100

WB: 1:1000 ICC/IF: 1:100 FC: 1:20 IP: 1:20

120kDa

97kDa

-20°C/1 year

Rabbit

IgG

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Affinity Purification