产品名称
PDCD5 Rabbit Polyclonal Antibody
蛋白名称
Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O14737
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14737/entry
Mouse Swissprot No.
P56812
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P56812
免疫原
Synthesized peptide derived from part region of human protein
特异性
PDCD5 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010],
组织表达
Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.
细胞定位
nucleus,cytoplasm,cytosol,extracellular exosome,
功能
developmental stage:Expression in fetal tissues is significantly lower than in adult tissues.,function:May function in the process of apoptosis.,induction:Activated in cells undergoing apoptosis.,similarity:Belongs to the PDCD5 family.,tissue specificity:Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
