RM3698

Dnmt1 (12Y11) Rabbit Monoclonal Antibody

AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; m.HsaI

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human Dnmt1

WB: 1:2000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20

183kDa

183kDa

-20°C/1 year

Rabbit

IgG

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Affinity Purification