RM3685

NMDAR2B (5P4) Rabbit Monoclonal Antibody

NR2B; GluN2B; Nmdar2b; AW490526

常规抗体

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of mouse NMDAR2B

WB: 1:1000

166kDa

166kDa

-20°C/1 year

Rabbit

IgG

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death.

Affinity Purification