RM3622

Cathepsin D (4H13) Rabbit Monoclonal Antibody

CPSD; CLN10; HEL-S-130P

常规抗体

WB

Human,Mouse

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human Cathepsin D

WB: 1:2000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20

45,43,28kDa

45kDa

-20°C/1 year

Rabbit

IgG

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]

Affinity Purification