产品名称
PU.1/Spi1 (14U16) Rabbit Monoclonal Antibody
别名
OF; PU.1; SFPI1; SPI-1; SPI-A
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic peptide of human PU.1/Spi1
稀释度
WB: 1:1000 IHC: 1:20-1:50 ICC/IF: 1:20-1:100 FC: 1:20
背景介绍
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]