RM3545

p57 Kip2 (4L10) Rabbit Monoclonal Antibody

BWS; WBS; p57; BWCR; KIP2; p57Kip2

常规抗体

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human p57 Kip2

WB: 1:1000 IHC: 1:100 ICC/IF: 1:100 FC: 1:50 IP: 1:20

57kDa

32kDa

-20°C/1 year

Rabbit

IgG

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Affinity Purification