RM3542

PDX1 (2F4) Rabbit Monoclonal Antibody

GSF; IPF1; IUF1; IDX-1; MODY4; PDX-1; STF-1; PAGEN1

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human PDX1

WB: 1:1000 IHC: 1:100 ICC/IF: 1:20-1:100

42kDa

31kDa

-20°C/1 year

Rabbit

IgG

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]

Affinity Purification