RM3534

SCRIBBLE (1T14) Rabbit Monoclonal Antibody

CRIB1; SCRB1; SCRIB1; Vartul

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human SCRIBBLE

WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50

240kDa

175kDa

-20°C/1 year

Rabbit

IgG

This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Affinity Purification