产品名称
IFNA2 Rabbit Polyclonal Antibody
蛋白名称
Interferon alpha-2 (IFN-alpha-2) (Interferon alpha-A) (LeIF A)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P01563
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P01563/entry
Mouse Swissprot No.
P01573
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P01573
免疫原
Synthesized peptide derived from part region of human protein
特异性
IFNA2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011],
组织表达
Bone marrow tumor,PCR rescued clones,Placenta,Pooled tissue,
信号通路
Cytokine-cytokine receptor interaction;Regulation of autophagy;Antigen processing and presentation;Toll_Like;RIG-I-like receptor;Cytosolic DNA-sensing pathway;Jak_STAT;Natural killer cell mediated cytotoxicity;Autoimmune thyroid disease;
功能
function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,pharmaceutical:Available under the names Roferon-A (Roche) or Intron-A (Schering-Plough). Used as an anticancer drug for its antiproliferative activity.,polymorphism:Three forms exist; alpha-2a (shown here), alpha-2b and alpha-2c.,similarity:Belongs to the alpha/beta interferon family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
