RM3447

Cathepsin K (18M18) Rabbit Monoclonal Antibody

CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Recombinant protein of human Cathepsin K

WB: 1:1000 IHC: 1:200

37kDa

37kDa

-20°C/1 year

Rabbit

IgG

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]

Affinity Purification