产品名称
GRIP2 Rabbit Polyclonal Antibody
蛋白名称
Glutamate receptor-interacting protein 2 (GRIP-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9C0E4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9C0E4/entry
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9WTW1
免疫原
Synthesized peptide derived from human protein . at AA range: 780-860
特异性
GRIP2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.,function:May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.,similarity:Belongs to the GRIP2 family.,similarity:Contains 7 PDZ (DHR) domains.,subunit:Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR.,
细胞定位
Cytoplasm . Membrane ; Peripheral membrane protein .
功能
domain:PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.,function:May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.,similarity:Belongs to the GRIP2 family.,similarity:Contains 7 PDZ (DHR) domains.,subunit:Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
