产品名称
PKR (16X15) Rabbit Monoclonal Antibody
别名
PKR; PRKR; EIF2AK1; PPP1R83
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic peptide of human PKR
稀释度
WB: 1:1000-1:2000 IHC: 1:100 ICC/IF: 1:20-1:100 FC: 1:20 IP: 1:20-1:50
背景介绍
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
