RM3363

TNFRSF18 (11O5) Rabbit Monoclonal Antibody

AITR; GITR; CD357; GITR-D

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human TNFRSF18

WB: 1:1000 IHC: 1:200 ICC/IF: 1:100

26kDa

26kDa

-20°C/1 year

Rabbit

IgG

y This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

Affinity Purification