RM3361

Ku80 (19N5) Rabbit Monoclonal Antibody

KU80; KUB2; Ku86; NFIV; KARP1; KARP-1

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human Ku80

WB: 1:1000-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50-1:100 FC: 1:20 IP: 1:20

83kDa

83kDa

-20°C/1 year

Rabbit

IgG

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Affinity Purification