产品名称
GBP2 Rabbit Polyclonal Antibody
蛋白名称
Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P32456
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P32456/entry
Mouse Swissprot No.
Q9Z0E6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9Z0E6
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q63663
免疫原
Synthesized peptide derived from human protein . at AA range: 160-240
特异性
GBP2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013],
组织表达
Foreskin,Lung,Skin,Spinal cord,Thymus,
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Membrane; Lipid-anchor . Cytoplasmic vesicle . GBP2-GBP5 dimers localize to the Golgi apparatus. .
功能
function:Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product.,induction:By interferon gamma during macrophage activation.,similarity:Belongs to the GBP family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
