产品名称
Apolipoprotein E (4Y14) Rabbit Monoclonal Antibody
别名
AD2; LPG; APO-E; ApoE4; LDLCQ5
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic peptide of mouse Apolipoprotein E
稀释度
WB: 1:1000 IHC: 1:200-1:1000 ICC/IF: 1:100 FC: 1:20 IP: 1:20
背景介绍
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
