产品名称
COX7R Rabbit Polyclonal Antibody
基因名称
COX7A2L COX7AR COX7RP
蛋白名称
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7a-related protein) (Cytochrome c oxidase subunit VIIa-related protein) (EB1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O14548
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14548/entry
Mouse Swissprot No.
Q61387
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61387
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
COX7R Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target
组织表达
Lung,Placenta,Prostate,Spleen,
细胞定位
Mitochondrion inner membrane .
信号通路
Oxidative phosphorylation;Cardiac muscle contraction;Alzheimer's disease;Parkinson's disease;Huntington's disease;
功能
function:May be a regulatory subunit of cytochrome c oxidase that mediates the higher level of energy production in target cells by estrogen.,induction:By estrogen.,similarity:Belongs to the cytochrome c oxidase VIIa family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
