产品名称
CCBE1 Rabbit Polyclonal Antibody
基因名称
CCBE1 KIAA1983 UNQ1921/PRO4395
蛋白名称
Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6UXH8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6UXH8/entry
Mouse Swissprot No.
Q3MI99
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3MI99
免疫原
Synthesized peptide derived from human protein . at AA range: 120-200
特异性
CCBE1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans. [provided by RefSeq, Mar 2010],
组织表达
Not expressed in blood or lymphatic endothelial cells.
功能
function:Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.,similarity:Belongs to the CCBE1 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 collagen-like domains.,tissue specificity:Not expressed in blood or lymphatic endothelial cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
