产品名称
CDY1 Rabbit Polyclonal Antibody
蛋白名称
Testis-specific chromodomain protein Y 1 (EC 2.3.1.48)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9Y6F8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y6F8/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 210-290
特异性
CDY1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined. [provided by
组织表达
Testis-specific. Detected in spermatids (at protein level).
功能
catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Has histone acetyltransferase activity, with a preference for histone H4.,similarity:Contains 1 chromo domain.,tissue specificity:Testis specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.