产品名称
XPB (2A10) Rabbit Monoclonal Antibody
别名
XPB; BTF2; TTD2; GTF2H; RAD25; TFIIH
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
免疫原
A synthetic peptide of human XPB
稀释度
WB: 1:1000-1:5000 IHC: 1:100 ICC/IF: 1:100
背景介绍
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]