RM3138

Ku70 (4E7) Rabbit Monoclonal Antibody

ML8; KU70; TLAA; CTC75; CTCBF; G22P1

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human Ku70

WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:50

70kDa

70kDa

-20°C/1 year

Rabbit

IgG

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Affinity Purification