产品名称
TNF18 Rabbit Polyclonal Antibody
基因名称
TNFSF18 AITRL GITRL TL6 UNQ149/PRO175
蛋白名称
Tumor necrosis factor ligand superfamily member 18 (Activation-inducible TNF-related ligand) (AITRL) (Glucocorticoid-induced TNF-related ligand) (hGITRL)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UNG2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UNG2/entry
Mouse Swissprot No.
Q7TS55
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TS55
免疫原
Synthesized peptide derived from part region of human protein AA range: 101-150
特异性
TNF18 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008],
组织表达
Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
细胞定位
Cell membrane ; Single-pass type II membrane protein .
信号通路
Cytokine-cytokine receptor interaction;
功能
function:Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.,induction:Up-regulated after stimulation by lipopolysaccharides.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer .,tissue specificity:Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
