产品名称
SYWM Rabbit Polyclonal Antibody
蛋白名称
Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UGM6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UGM6/entry
Mouse Swissprot No.
Q9CYK1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CYK1
免疫原
Synthesized peptide derived from part region of human protein
特异性
SYWM Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix .
信号通路
Tryptophan metabolism;Aminoacyl-tRNA biosynthesis;
功能
catalytic activity:ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).,similarity:Belongs to the class-I aminoacyl-tRNA synthetase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.