RM3083

Phospho-Cdc6 (Ser106) (12Q3) Rabbit Monoclonal Antibody

CDC18L; HsCDC6; MGORS5; HsCDC18

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6

WB: 1:1000

63kDa

63kDa

-20°C/1 year

Rabbit

IgG

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]

Affinity Purification