RM3062

68kDa Neurofilament (12J19) Rabbit Monoclonal Antibody

NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110

常规抗体

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Recombinant protein of mouse 68kDa Neurofilament

WB: 1:1000 IHC: 1:200 IP: 1:20

68kDa

62kDa

-20°C/1 year

Rabbit

IgG

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

Affinity Purification