产品名称
TSSC4 Rabbit Polyclonal Antibody
蛋白名称
Protein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9Y5U2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y5U2/entry
Mouse Swissprot No.
Q9JHE7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JHE7
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5XIB1
免疫原
Synthesized peptide derived from part region of human protein
特异性
TSSC4 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes; however, this gene, as well as the pan-hematopoietic expression gene (PHEMX), escapes imprinting. This gene may play a role in malignancies and disease that involve this region. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
组织表达
Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues.
功能
similarity:Belongs to the TSSC4 family.,tissue specificity:Expressed in fetal brain, lung, liver and kidney. Widely expressed in adult tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
