RM2982

Lin28A (11V3) Rabbit Monoclonal Antibody

CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A

常规抗体

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

A synthetic peptide of human Lin28A

WB: 1:2000-1:10000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20

23kDa

23kDa

-20°C/1 year

Rabbit

IgG

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

Affinity Purification